Hepatoprotective Activity on Vitex negundo Linn. (Verbenaceae) by using Wistar Albino Rats in Ibuprofen Induced Model
نویسندگان
چکیده
منابع مشابه
Antinociceptive activity of Vitex-negundo Linn leaf extract.
Tail flick test in rats and acetic acid induced writhing in mice were employed to study the antinociceptive activity of ethanolic leaf extract of Vitex-negundo (VN) (100, 250 and 500 mg/kg, p.o). The effect was compared with meperidine (40 mg/kg, sc) in tail flick method and aspirin (50 mg/kg, p.o) in writhing test as a standard control respectively. An interaction with naloxone hydrochloride w...
متن کاملPharmacokinetic-interaction of Vitex negundo Linn. & paracetamol.
BACKGROUND & OBJECTIVES Currently, herbal preparations are clinically used as functional food, food supplements or as add on therapy, which affects the bioavailability and also the net therapeutic potential of co-administered allopathic drugs. Therefore, it is important to assess the interaction among these two classes of drugs. Here we studied the interaction between orally-administered ethano...
متن کاملHepatoprotective Role of Ethanolic Extract of Vitex negundo in Thioacetamide-Induced Liver Fibrosis in Male Rats
The hepatoprotective activity of ethanolic extract from the leaves of Vitex negundo (VN) was conducted against thioacetamide- (TAA-) induced hepatic injury in Sprague Dawley rats. The therapeutic effect of the extract was investigated on adult male rats. Rats were divided into seven groups: control, TAA, Silymarin (SY), and VN high dose and low dose groups. Rats were administered with VN extrac...
متن کاملComparative Study of the Hepatoprotective Activities of Vitex Negundo Linn. and Moringa Oleifera Lam. in Paracetamol Induced Hepatotoxicity in Experimental Animals
Aims: To evaluate the hepatoprotective activity of Vitex negundo Linn. and Moringa oleifera Lam. In paracetamol induced hepatotoxicity in rats. Materials and Methods: Liver damage was induced in 42 albino rats by paracetamol (1 g/kg P.O.) once daily for a period of 7 days. Silymarin was taken as the standard drug in a dose of 25 mg/kg P.O. Albino Wistar rats (150-200 g) were divided into groups...
متن کاملHepatoprotective Activity of Adhatoda vasica and Vitex negundo Leaf Extracts Against Carbon Tetrachloride Induced Hepatotoxicity in Rats
Liver diseases such as jaundice, cirrhosis etc. are very common worldwide and traditional medicine are proving to be useless or less effective against them. Therefore workers are trying to find out alternate medicine or formulations to combat these diseases. In the present study hepatoprotective activity of aqueous extract of Adhatoda vasica and Vitex negundo on total protein, bilirubin, aspart...
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ژورنال
عنوان ژورنال: International Journal of Pharmacology
سال: 2010
ISSN: 1811-7775
DOI: 10.3923/ijp.2010.658.663